Genetic renegades: the B chromosomes of D. melanogaster

The Hanlon Lab studies how chromosomes move, form, and evolve. Our model system is the newly discovered B chromosomes in the fruit fly Drosophila melanogaster. B chromosomes are extra, nonessential chromosomes that have been found in hundreds of different plant and animal species and can promote their own segregation, sometimes to the detriment of their host. The Hanlon Lab applies a multitude of cellular, molecular, and genetic tools available in D. melanogaster to understand how B chromosomes rendezvous and segregate during cell division. We also investigate the intrinsic biology of these young B chromosomes, including their effects on life history traits, the frequency of their formation, and the flux of their heterochromatic repeat and transposable element composition over time.
Another un-B-lievable year in the Hanlon Lab! Thanks for all your hard work and making the lab a great place to B!

Clockwise, from bottom left: Michelle, Kaylah, Haneesh, Natalie, Robin, Stacey, Shania, Edward, Annette, Abby, and Suparna (not pictured: Paul).

Another un-B-lievable year in the Hanlon Lab! Thanks for all your hard work and making the lab a great place to B!

Clockwise, from bottom left: Michelle, Kaylah, Haneesh, Natalie, Robin, Stacey, Shania, Edward, Annette, Abby, and Suparna (not pictured: Paul).
...

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The Hanlon Lab had a B-witching time B-ing the crew from Inside Out 2 for Halloween! Such a creative bunch of scientists!

The Hanlon Lab had a B-witching time B-ing the crew from Inside Out 2 for Halloween! Such a creative bunch of scientists! ...

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Congratulations to Annette, an un-B-lievable undergrad in the lab, on her first poster presentation! She described her UConn SURF-sponsored research investigating how oocyte age affects B chromosome transmission. Great job!

Congratulations to Annette, an un-B-lievable undergrad in the lab, on her first poster presentation! She described her UConn SURF-sponsored research investigating how oocyte age affects B chromosome transmission. Great job! ...

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Haneesh J had an awesome rotation and helped put the "B" in Bioinformatics! Thanks for rotating through the Hanlon Lab!

Haneesh J had an awesome rotation and helped put the "B" in Bioinformatics! Thanks for rotating through the Hanlon Lab! ...

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Great RIPS talk, Shania! Now everyone knows how these chromosomes came to 'B'...

Great RIPS talk, Shania! Now everyone knows how these chromosomes came to `B`... ...

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Meet the “B” Team!

Meet the “B” Team! ...

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